ULK1 anticorps (AA 11-312)

N° du produit ABIN7140916

Cet anticorps anti-ULK1 est un anticorps Lapin Polyclonal détectant ULK1 dans ELISA. Adapté pour Candida glabrata.

Aperçu rapide pour ULK1 anticorps (AA 11-312) (ABIN7140916)

Antigène: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Reactivité: Candida glabrata

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ULK1 est non-conjugé

Application: ELISA

Détail du produit anti-ULK1 anticorps

Épitope: AA 11-312

Fonction: ATG1 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Candida glabrata Serine/threonine-protein kinase ATG1 protein (11-312AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ULK1

Antigène: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Autre désignation: ATG1

Sujet:

Background: Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates. Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.

Aliases: ATG1 antibody, CAGL0L06006g antibody, Serine/threonine-protein kinase ATG1 antibody, EC 2.7.11.1 antibody, Autophagy-related protein 1 antibody

UniProt: Q6FL58

Pathways: Regulation of Cell Size, Autophagy